Triple Negative Breast Cancer (TNBC) is a type of breast cancer that is more aggressive and difficult to treat than other types of breast cancer.
It is called triple negative because it does not respond to the three most common receptors targeted by breast cancer treatment: estrogen, progesterone, and HER2/neu. As a result, TNBC does not respond to hormonal therapies or drugs that target these receptors, making it more challenging to treat.
TNBC accounts for about 15% of all breast cancer cases and is more common in younger women and African American women.
March 3rd is recognized as Triple Negative Breast Cancer Awareness Day to raise awareness about this type of breast cancer and the challenges it poses.
Here are some key facts and information about TNBC:
- Symptoms: The symptoms of TNBC are similar to other types of breast cancer and can include a lump or swelling in the breast, nipple discharge, or changes in the breast skin or shape. Women should regularly perform self-exams and schedule mammograms as recommended by their healthcare provider.
- Diagnosis: TNBC is diagnosed through a biopsy, where a small amount of breast tissue is removed and examined for cancer cells. If TNBC is diagnosed, further testing may be done to determine the stage of the cancer and the best treatment options.
- Treatment: Treatment for TNBC typically involves a combination of surgery, chemotherapy, and radiation therapy. Because TNBC does not respond to hormonal therapies or drugs that target estrogen, progesterone, or HER2/neu receptors, these treatments are not effective. Clinical trials are ongoing to explore new treatment options for TNBC.
- Prevention: Women can reduce their risk of developing TNBC by maintaining a healthy lifestyle, including regular exercise and a healthy diet, limiting alcohol consumption, and avoiding tobacco use. Women at high risk for breast cancer may also consider genetic counseling and testing.
Triple Negative Breast Cancer Awareness Day serves as a reminder of the importance of breast cancer awareness and early detection. By increasing awareness and understanding of TNBC, we can improve outcomes for those affected by this aggressive form of breast cancer.
